By using our services, you agree to our use of cookies. Antispasmodic activity: A 50% ethanolic extract of Paederia foetida exhibited antispasmodic activity on the isolated guinea pig ileum. Chinese moon creeper, Chinese fevervine, kings tonic (En), Indonesia: sembukan (Javanese), kahitutan (Sundanese), bintaos (Madurese), Malaysia: akar sekentut, daun kentut, kesimbukan, Philippines: kantutai (Tagalog), bangogan (Bikol), mabolok (Pampangan), Thailand: kon, choh-ka-thue mue (northern), yaan phaahom (peninsular). The water-soluble fraction was found to be non-toxic up to 2 g/kg (PO and IP) in rats and mice and it exerted no significant effect on gross general behaviour. Several iridoid glucosides containing an intramolecular lactone ring, i.e. Paederia foetida medicinal uses: • Anti-inflammatory activity: It has anti-inflammatory properties and is useful in the treatment of edema and all other inflammatory conditions. Kapadia, G.J., Sharma, S.C., Tokuda, H., Nishino, H. & Ueda, S., 1996. The activity was dose dependent and showed a remarkable increase when the extract was administered intra peritoneally. relieve distension due to flatulence and in herpes infections. In some parts of India, the fruit is used to blacken teeth, and it is also considered a medicine to prevent toothache. (Rubiaceae), Journal of Ethnopharmacology, 105, 125–130. P. foetida is harvested from the wild whenever needed. The Paederia Foetidais known for treating ailments like colic, flatulence, gout, diarrhea, infertility, paralysis, rheumatism, abscesses, and dysentery. Purple or violet flowers are found in scorpioid cymes. Because of this it is regarded as a specific remedy for rheumatic conditions associated with stiffness and contraction of the joints. P. foetida is protrandrous and self-incompatible; stigmas remain receptive for a short period only. Antiarthritic activity: Paederia foetida extract was tested for its effect on osteoarthritis-like lesions induced in the knee joints of rabbits by ananase (the proteolytic enzyme from pineapple). Fitoterapia 65(4): 357-362. & Deka, P.C., 1999. Inflorescence a terminal or axillary cymose panicle, extremely variable, from widely branched paniculate, over 1 m long to rather reduced, 10 cm long; bracts foliaceous or small and linear, with few to numerous flowers, often in lax scorpioid cymes; peduncle 2-30 mm long. P. foetida is mainly propagated by seed. This suggests that a stimulation of the adrenal-pituitary axis is not involved. Revised reprint. Skunkvine also known as Paederia Foetida, is a fast growing vine having 7 m long stems that twine into other plants for support (climbs into tree canopies or crawls on the ground). The word meaning of Gandha Prasarini in Sanskrit is – it spreads bad smell! Anthelmintic activity: An aqueous extract administered orally was highly effective against Strongyloides, The genus Paederia L.: a multidisciplinary study. The whole plant shows tonic, astringent and antiphlogistic actions and has been used in tenesmus.Whole plant, leaves, roots. P foetida is also reported to have ethno medicinal uses … In addition, scandoside was found to promote the growth of lettuce seedlings. Paederia tomentosa Blume (1826), Paederia chinensis Hance (1878), Paederia scandens (Lour.) as a potential medicinal plant: a review. The plant is considered specific for treating rheumatism and all types of neurological diseases. Linalool is the major component of the oil obtained from the stem, leaf and flower, together with a-terpineol and geranio1.2 The leaf and stem also contain hentriacontane, hentriacontanol and ceryl alcohol, 2,3-dihydrobenzofuran, benzofuran and the sulphur-containing compounds dimethyl sulphide and dimethyl trisulphide. A slender, perennial, stinking twiner, 1.5-7 m long, branches dextrorsely twining, young stems purplish- or reddish-brown, glabrous to densely hairy, old stems glabrescent, shiny yellowish-brown to greyish. Damage to the tissue releases an enzyme which splits off this sulphur-containing group from paederoside, and is therefore responsible for the unpleasant odour. There are no known breeding programmes of P. foetida . Mekong Printing, Santa Ana, California, United States. For intestinal problems, fresh leaves are pounded, water added, and the … P. foetida occurs commonly as a ruderal in thickets and woodland, but also along forest edges, in secondary evergreen to deciduous forest and clearings in primary forest. Paederia foetida is a herb that has traditionally been used for a variety of purposes that seem to be centered around either intestinal health (particularly anti-diarrheal and anti-dysentry) and as an invigorator for male health. In Java, the leaves are also consumed as a vegetable, when mixed with grated coconut and spices. 1241-2444. The LDso of a 50% ethanolic extract of leaves was 1200 mg/kg in mice. It has been used in Ayurvedic medicines which has been used since ages for different purposes. It reduced the degradation changes in the articular cartilage induced by ananase and in vitro studies using ananase-treated chick embryonic bones showed that the plant (at a dose of 10 mg/ml of the medium) enhanced … 2 (I-Z) pp. Paederia foetida is a potential medicinal plant [2, 3] P. foetida is usually used as remedy for diarrhoea and dysentery and major chemical constituents like asperuloside, scandoside, paederoside and a-and b-paederine etc. The northeastern region of India constitutes one of the biodiversity hotspots of the world. Found in the Himalayas from Dehradun eastwards, up to an altitude of 1800 m. It is also found in Bihar, Orissa, Bengal and Assam. Asperuloside was also isolated from other Rubiaceae , including Asperula odorata L. and several Coprosma species. Considered to have medicinal properties for treating stomach ache and gastric problems. The plant is considered to have great restorative powers, and the leaves may thus be mixed with food, boiled and eaten. About 70% of these plantlets were successfully transferred to soil. Puff, C. (Editor), 1991. Paederoside showed a similar inhibitory activity to that of asperuloside and daecetyl-asperulosidic acid in a plant growth inhibition test and in an antimicroorganism activity test. Council of Scientific and Industrial Research, 1948-1976. Medicinal and poisonous plants. a-Paederine and ?-paederine have been isolated. Single intraperitoneal injection (IP) of streptozotocin (60 mg/kg body weight) was used for induction of diabetes is swiss albino (wistar strain) rats. It is a host for the root-knot nematode Meloidogyne sp. The leaves, in the form of a poultice, are applied to the abdomen to . In this study, experiments were designed to develop regeneration protocols for the propagation as well as conservation of a rare medicinal plant, Paederia foetida (L.) The leaves are antirheumatic. From the iridoids isolated, paederoside displayed the highest order of antitumour-promoting activity. However, the status remained unaltered in carrageenan-induced oedema in adrenalectomized rats. (PF) leaf extract in the streptozotocin induced diabetic rats. The results also demonstrate that the plant extract possesses cytotoxic activities. The results suggest that the plant extract has analgesic and antidiarrhoeal activities, supporting its uses in traditional medicine. The genus Paederia L. (Rubiaceae-Paederieae): a multidisciplinary study. Opera Botanica Belgica 3: 167 -178. It significantly enhanced the humoral antibody synthesis and early hypersensitivity (4 h) reaction but slightly inhibited the development of 24 h reaction. Nguyen Van Duong, 1993. The fruits are used to prevent toothache. "P. foetida is mainly propagated by seed." The name P. foetida has been used for 2 different species, which are very similar vegetatively and in flower, but are strikingly different in fruit. The leaves are also used to treat hepatic disorders and rheumatism. Singh, S., Bani, S., Khajuria, A., Sharma, M.L., Singh, G.B., Suri, K.A. The leaves and stems are also used as a diuretic for inflammation of the urethra, or they are mashed and applied for earache, ulcerations of the nose and swollen eyes. References : Afroz, S. et al., (2006), Antidiarrhoeal activity of the ethanol extract of Paederia foetida Linn. In America, only Alatopaederia occurs, 1 species is endemic to Mexico, the other occurs throughout South America. However, still very little is known about possible compounds involved in these activities, and therefore more research is needed to fully evaluate the potential. The primary objective of the present investigation is to evaluate the antidiabetic, antihyperlidemic and antioxidant activity of the methanolic extract of the Paederia foetida Linn. Flowers bisexual, usually 5-merous, dirty pink or lilac, or purplish, corolla lobes pinkish to whitish inside, throat dark purple; calyx campanulate, 5-lobed, lobes triangular, up to 1 mm × 0.6 mm, normally glabrous; corolla cylindrical to bell-shaped, 5-17 mm × 2-5 mm, throat and inside of tube densely long-hairy, lobes 5, oblong to triangular, 1-3 mm × 1.5-3 mm, margins wavy, inflexed; stamens 5, inserted in the middle of the tube, included, anthers 2-2.5 mm long; ovary inferior, 2-celled, 2-ovuled, disk small, style and stigmas 4-15 mm long, joined style part up to 2 mm long, stigma branches 2, filiform, irregularly twisted, mostly included. Opera Botanica Belgica 3: 1-376. LD50was found to be greater than 2 g/kg in rats and mice upon oral as well as intraperitoneal treatments. "Paederia foetida — a promising ethno-medicinal tribal plant of northeastern India" Save as: AGRIS_AP RIS EndNote(XML) Ayurvedic medicine with Paederia foetida- Prasarini Thailam – used in arthritis, sciatica etc. Fruit a drupe, (sub)globose, 4-6 mm in diameter, walls thin, dry, brittle, crowned by the persistent sepals, shiny pale brown to yellowish- or reddish-brown; pyrenes 2, semi-orbicular or semi-ellipsoidal, plano-convex or compressed, slightly smaller than fruit, without conspicuous wings, black, often conspicuously covered with raphides. The root is cylindrical or sub cylindrical and compressed on both sides, with an outer surface covered in root scars. They are used to increase infertility and treat paralysis. The latter compound also contains an unusual S-methylcarbonate function. Journal of Ethnopharmacology 43(1): 31-38. Publications and Information Directorate, New Delhi, India.236, 250, 264, 331, 407, 552, 786, 788, 803, 810, 841, 926, 1076. P. foetida, which grows mainly in China, Bangladesh, India and Mauritius, has been used in folk medicine for the treatment of inflammation, piles, and diarrhea, while P. scandens is used to treat aches, jaundice, dysentery and dyspepsia as a folk medicine in the southern region of China, Vietnam, India and Japan. The stem yields a strong and silky fibre, but it is not commercially exploited. The ethnic groups inhabiting this region practice their distinctive traditional knowledge systems using biodiversity for food, shelter and healthcare. Parts of P. foetida are mainly used fresh, but can be dried for later use. Antiarthritic activity: Paederia foetida extract was tested for its effect on osteoarthritis-like lesions induced in the knee joints of rabbits by ananase (the proteolytic enzyme from pineapple). Bruised aerial parts of the plant have the fetid odour of indole (methyl-mercaptan). There is very limited evidence to … Sometimes, shoots produce adventitious roots when they come in contact with the soil, and can thus be propagated as well. Medicinal plants of Vietnam, Cambodia and Laos. This fraction produced a significant inhibition of granulation tissue formation in cotton-pellet implanted rats. Asperuloside, paederoside and scandoside have been isolated from the leaf and stem. Monoterpenes such as linalol constitute the major components in the oil. Ministry of Agriculture and Co-operatives, Kuala Lumpur, Malaysia. The water soluble fraction of the aerial parts displayed anti-inflammatory activity in carrageenan-, dextran- and histamine-induced oedema in rats and mice. The wealth of India: a dictionary of Indian raw materials & industrial products. Paederia foetida is an indigenous plant belongsto family Rubiaceae. P. foetida is widespread and common throughout South-East Asia, and is not at risk of genetic erosion. The plant is having a broad spectrum of use as in treatment of hepatic disorders, rheumatoid arthritis, The leaves of P. foetida are widely used in Asia and South-East Asia for the treatment of intestinal complaints such as colic, cramps, flatulence, dysentery and also for rheumatism and gout. The leaves are anodyne, antirheumatic, antivinous, astringent, carminative, depurative, diuretic, restorative and vermifuge [147, 218, 310 ]. In Ayurveda, the plant is used for treatment of arthritis, disorders of heart and kidney and it also serves as a widely used pain relieving massage oil. (1934). The presence of alkaloids (α- andβ-paederine, aerial parts) and an essential oil have also been recorded. Finally, the ethanolic extract of the leaves and stem was significantly toxic against the aphid Myzus persicae infesting cabbage, in India. Vol. Paederia is divided into 3 subgenera, of which all species of the subgenus Paederia and the majority of the species belonging to the subgenus Alatopaederia occur in South-East Asia. The leaf and stem contain sitosterol, stigmasterol and campesterol. Seedling with epigeal germination; cotyledons broadly rounded, veins prominent; first pair of leaves elliptical, apex acuminate. Backhuys Publishers, Leiden. 11 volumes. Triterpenoids and saponins Ursolic acid, epifriedelinol, friedelin. It failed to exhibit any analgesic or antipyretic action and showed no ulcerogenic potential. In Peninsular Malaysia and Java they are applied to swellings and bruises in general. Extracts of P. foetida show interesting activities in the field of anti-inflammation, which could be of interest for the development of future active substances to be used in the treatment of rheumatic complaints. In older investigations, decoctions of the plant showed significant anti-inflammatory action against formaldehyde-induced arthritis in non-adrenalectomized albino rats. An extensive climber, leaves ovate to lanceolate, entire, about 5 cm long and 2.5 cm broad, membranous with long petioles. Paederia foetida and P. scandens are two important and well explored Paederia species (Rubiaceae). The leaves of P. foetida are widely used in Asia and South-East Asia for the treatment of intestinal complaints such as colic, cramps, flatulence, dysentery and also for rheumatism and gout. Photochemical Screening of Paederia Foetida a rare medicinal plant - A review made by [15,16] studied anti-diarrhoeal potential of Paederia foetida. A decoction of the whole plant is used in the treatment of abdominal pain, abscesses, arthritis, overeating etc[147, 218]. The antioxidant activity of fresh and dried plant extracts of Paederia foetida and Syzygium aqueum were studied using β-carotene bleaching and the 2,2’-azinobis(3-ethyl-benzothiazoline-6-sulfonic acid) (ABTS) radical cation assay. They are commonly used for the treatment of intestinal complaints such as abdominal pain, colic, cramps, flatulence and dysentery; and are also used for treating rheumatism and gout [. In: Puff (ed.) ... Paederia foetida L. . Micropropagation is also successful. CONCLUSION: The available scientific research on Paederia foetida has shown that it is an important medicinal plant used in a wide range of ethnomedical treatments, especially for constipation, stomachache, dysentery, blood disorders, broken or fractured bones and sprains. • Anti-arthritic activity: It is very useful in the treatment of joint problems like arthritis and joint pain, gout etc. In India, the leaves are often boiled in soup to lessen their smell. Investigation of the anti-inflammatory effects of Paederia foetida. 12(2). 367-368. 2 volumes. The main use The main use of the plant is for arthritis and:rheumatic disorders. Singh, S., Ray, B.K., Mathew, S., Buragohain, P., Gogoi, J., Gogoi, S., Sharma, B.K. It is extensively used in … The hepatoprotective potential of a leaf methanol extract has been assessed against CCl4-induced liver damage in the rat model. Paederia foetida, biodiversity, foods, gastrointestinal system, health services, indigenous knowledge, lifestyle, medicinal properties, medicine, nationalities and ethnic groups, new drugs, plant biochemistry, India Abstract: The northeastern region of India constitutes one of the biodiversity hotspots of the world. It also decreased liver (but not serum) aspartate transaminase activity but did not affect adrenal weight and ascorbic acid content significantly. In the Philippines, the bark or the root is considered emetic, and the leaves are used in antirheumatic baths. Bees and butterflies have been observed to visit the flowers. Cancer Letters 102(1-2): 223-226. In Peninsular Malaysia, the juice of the leaves is considered astringent, and is given to children for diarrhoea. It significantly enhanced humoral antibody synthesis and the early hypersensitivity reaction, but slightly inhibited development of the 24 hour reaction. It did not, however, affect adrenal weight or ascorbic acid content significantly, thus ruling out a stimulation of the adrenal-pituitary axis. As per the properties and functions of the herb it is used in healing the problems related to intestinal health (particularly anti-diarrheal and anti-dysentery) and as a support for male health. MEDICINAL VALUES OF SKUNK VINE (Paederia foetida L.)-AN OVERVIEW Home | About Us | Herbs A to Z | Terms & Conditions | Contact Us, Copyright © Krishna Herbal Company 2018. 6.03 Puff (1991) Selected aspects of the reproductive biology of Paederia L. (Rubiaceae - Paederieae). Burkill, I.H., 1966. P. foetida has (sub)globose fruits and a very wide distribution in South-East Asia while P. cruddasiana Prain has laterally compressed-ovoid fruits, which are distinctly winged, and which occurs from northern India, Bangladesh, Nepal, Bhutan to south-western China and Thailand. Annals of Biology Ludhiana 15(1): 1-7. Hepatoprotective activity: The methanol extract showed moderate hepatoprotective activity. The bark, leaf, root and whole plant have been used to treat maggots in wounds, abscesses, urethral calculi, repeat oestrus in cows and buffaloes, asthma, diarrhoea, constipation and expulsion of the placenta after miscarriage. They are used to increase infertility and treat paralysis. Maha Narayan Oil – widely used pain relieving massage oil Marma Gulika– used in disorders of heart, kidney etc. asperuloside, scandoside and paederoside were isolated from the aerial parts of P. foetida . Other biological activities include in vitro anticancer activity by an ethanolic extract of the leaves against human epidermoid carcinoma of the nasopharynx in tissue culture. Paederia foetida is known for the strong, sulphurous odour exuded when its leaves or stems are crushed or bruised. & Bhavsar, G.C., 1994. P. foetida is found from North-East India to China and Japan, southwards to Thailand, Malaysia, Indonesia and the Philippines. 147. Especially the disease-modifying component merits attention. P. foetida can be found flowering and fruiting throughout the year in tropical and subtropical conditions; in other localities, it flowers during the rainy season, and fruits early in the dry season. 1 (A-H) pp. It also inhibited the elevation of serum orosomucoid levels in rats, suggesting the possibility of the presence of disease-modifying antirheumatic activity. The extract antagonized hyposaline-induced haemolysis of human red blood cells and an elevation of rat serum acid phosphatase activity, indicating the presence of a membrane stabilizing activity. The leaves are antirheumatic. Over the past decade, herbal and ayurvedic drugs have become a subject of world importance, with both medicinal and economical implications. Medical uses of Paederia foetida are mainly for intestinal health and to aid in the control of bowel function such as, anti-diarrheal and anti-dysentry. Gandha Prasarini (Paederia foetida) is an important Ayurvedic medicinal herb. A dictionary of the economic products of the Malay Peninsula. Root induction was observed in MS media supplemented with 0.25 mg BAP + 0.5 mg indole butyric acid (IBA) within 12 days of culture. The intense odour is due to methyl mercaptan. It also exhibited marked activity against annanase-induced degenerative osteo-arthritis. Individual flowers are short-lived, open early in the morning and fall off after 2 days; entire inflorescences, however, bear flowers for a long period of time. Gandha means, smell and prasarini means spreading. The extract showed effectiveness in reversing 6 out of 12 common biochemical (enzymatic) parameters assessed. It has been introduced into North America (North Carolina, Texas, Louisiana), Hawaii, Christmas Islands, Mauritius and Reunion as an ornamental and escaped. Cookies help us deliver our services. Furthermore, the in vitro antitumour-promoting effect of a methanolic extract containing the iridoids was tested against the Epstein-Barr virus. 1-1240, Vol. More recently, the anti-inflammatory activity of the butanol fraction of a methanol extract of the defatted leaves of P. foetida was tested. Paederia foetida Linn. In Java, the leaves are applied as a poultice for a swollen belly, distension, herpes or ringworm. The root is also used as an emetic. Paederia is a small genus of 30 species distributed in Asia and South-East Asia (16 species), Africa and Madagascar (12 species) of which 11 are endemic to Madagascar, and America (2 species). A regular and widespread use of herbs throughout the world has increased serious concerns over their quality, safety and efficacy. For intestinal problems, fresh leaves are pounded, water added, and the filtered infusion is drunk regularly till convalescence. ]. The leaves of this plant have been excessively used in parts of Eastern Asian to help relieve herpes infections. The leaves can be mixed in omelettes as well for intestinal mucus. The leaves are rich in carotene and vitamin C. Antiinflammatory activity: A 50% ethanolic extract of P. foetida exhibited antiinflammatory activity traced to the water fraction, which demonstrated activity in various acute and chronic test models, such as carrageenan-, histamine- and dextran-induced oedema in rats. In India, the juice of the root is also prescribed in piles, inflammation of the spleen, and pain in the chest and liver. Anti-inflammatory activity of Paederia foetida. De, S., Ravishankar, B. In China, P. foetida is also used for the treatment of paralysis, to increase fertility, to help digestion, and also for insect bites. It also grows in montane vegetation up to 3000 m altitude, on steep, forested slopes, or on sandy or rocky sea coasts. The percentage of antioxidant activity for all extract samples using both assays was between 58 and 80%. Herb latin name: Paederia scandens Synonyms: Gentiana scandens, Paederia chinensis, Paederia foetida, Paederia tomemtosa Family: Rubiaceae (Madder Family) Medicinal use of Paederia scandens: The plant is anodyne, antivinous, carminative, depurative, vermifuge. The fracture is fibrous, the exterior brownish and the internal colour light brown, with a bitter taste. In Africa and Madagascar, 5 species belong to the subgenus Lecontea (all but 1 endemic to Madagascar), and the 6 other species of Madagascar belong to Alatopaederia . It is a unique feature of this herb. Multiple shoots were obtained from shoot tips (1-2 cm long) derived from field-grown plants of P. foetida in Murashige and Skoog (MS) medium supplemented with 1 mg benzyladenine (BAP)/l within 7 days of culture. All Rights Reserved Powered By: Planet Ayurveda, Infusion: 12-24 ml Decoction: 56-112 ml Powder: 2-4 g. An excellent, if rather terse, guide to the traditional medicinal uses of the plants of the region The root is mixed with gin and used as a treatment for back pain[ 348 The plant is grown in East Asia. The roots are used as an emetic and the juice extracted from the roots is given in cases of inflammation of the spleen and for pains in the chest and liver. Anticancer activity: The 50% ethanolic extract showed anticancer activity against human epidermoid carcinoma of nasopharynx in tissue culture. Paederia foetida L. is an important medicinal herb harboring lots of essential drug producing metabolites and the plant has been going to be endangered due to lack of proper strategies for conservation. It remained unaltered in carrageenan-induced oedema in adrenalectomised rats but in the carrageenan-induced pleurisy test in rats, it reduced pleural exudate volume and inhibited migration of leucocytes to the inflammatory site. It decreased liver aspartate transaminase activity without affecting serum aspartate transaminase activity. It reduced the degradation changes in the articular cartilage induced by ananase and in vitro studies using ananase-treated chick embryonic bones showed that the plant (at a dose of 10 mg/ml of the medium) enhanced the growth of the chick bones cultivated in this medium. Micropropagation of a few important medicinal plants. In Japan a feeding deterrent against the coccinellid Harmonia axyridis , produced by the aphid Acyrthosiphon nipponicus , which feeds exclusively on P. foetida , was identified as a paederoside. The herb has also been used to enhance sexual desire and as an aphrodisiac for centuries, which is what we’re going to look at today. In the carrageenan pleurisy test in rats, it reduced the pleural exudate volume and inhibited the migration of leucocytes into the inflammatory site. The unpleasant smell of the crushed leaves may play a role in superstitious beliefs, as it is associated with healing powers. No. Embelin has been isolated from the aerial parts. Whole plant is used in Indian System of Medicines. are present in this plant [4, 5, 6]. In India, P. foetida is attacked by Uredo paederiae causing rust, and also by Puccinia zoysiae causing leaf spot. Despite its weediness, P. foetida germinates rather slowly, and tetraploids germinate quicker than hexaploids, in 5-16(-22) days, or in 17-24 days, respectively. This is because the oil responsible for the smell, and found primarily within the leaves, contains sulphur compounds, including largely dimethyl disulphide. For fever, cloths soaked in the decoction are applied to the head, and the decoction is also given to drink. Paederia foetida L. (Family: Rubiaceae) is a perennial, twining medicinal plant emitting a displeasing foul odor due to the presence of methyl mercaptan in its leaves and stems [1]. pp. Uses. Activity was also observed in chronic models of adjuvant and formaldehyde arthritis in rats. Leaves decussate, simple, broadly ovate, elliptical-oblong to linear, 2-21 cm × 0.7-9 cm, base cordate, rounded or sometimes hastate, apex acute to acuminate, glabrous to variably hairy, sometimes indumentum whitish to golden yellow-brown; petiole 0.5-6(-9) cm long; stipules interpetiolar, rounded or ovate to triangular, 1.5-5 mm × 2-3 mm, usually entire, glabrous or hairy. The fruits are compressed, ellipsoid, red or black in colour. Lots of information on the uses of the plants of SE Asia. Thus people consumed the plant as local delicacy. The boiled and mashed leaves are applied to the abdomen as a diuretic, and also as a solvent for vesical stones. Vietnam: dây mơ lông, dây mơ tròn, mơ tam thể. Medicinal Uses. The most abundant sulphur-containing compound was dimethyl disulphide. The term prasarini (prasar = spread) indicates not only the spreading habit of the plant but the reputation of the drug for relaxing and 'spreading' parts of the body contracted by paralysis. P. foetida is used on a local scale only. In India and Indo-China, the stem, leaves and seeds are applied specifically for rheumatism, alone or in mixtures with other plants. It may help to eliminate poisons collected in the system. Among the less-studied plants, Paederia foetida has been used by various ethnic tribes as food and medicine. Merr. They are commonly used for the treatment of intestinal complaints such as abdominal pain, colic, cramps, flatulence and dysentery; and are also used for treating rheumatism and gout [147, 218, 310 ]. Inhibitory effect of iridoids on Epstein-Barr virus activation by a short-term in vitro assay for anti-tumor promoters. It has been found in Chinese herbalist shops in Peninsular Malaysia. The leaf contains a mixture of fatty acids including non-ionic, capric, lauric, myristic, arachidic and palmitic acids. & Srivastava, T.N., 1994. and moderately effective against Bunostomum and Monezia spp., when given at 2-day intervals in young calves. Another study reported that a butanol fraction of the leaves showed a significant antiinflammatory activity, producing a significant inhibition of granulation tissue formation in cotton pellet-implanted rats. Of heart, kidney etc medicinal uses of paederia foetida seedlings United States, southwards to Thailand, Malaysia the... Malaysia and Java they are used to treat hepatic disorders and rheumatism past,. An enzyme which splits off this sulphur-containing group from paederoside, and also by Puccinia causing! Soluble fraction of the biodiversity hotspots of the economic products of the adrenal-pituitary axis histamine-induced oedema in,. Terms & conditions | Contact Us, Copyright © Krishna herbal Company 2018 remarkable! The adrenal-pituitary axis is not medicinal uses of paederia foetida risk of genetic erosion 105, 125–130 the remained. Maha Narayan oil – widely used pain relieving massage oil Marma Gulika– used in arthritis, etc... Relieving massage oil Marma Gulika– used in ayurvedic medicines which has been found in scorpioid cymes this [. Humoral antibody synthesis and early hypersensitivity ( 4 h ) reaction but slightly inhibited development of the 24 reaction! Exhibited antispasmodic activity: an aqueous extract administered orally was highly effective against Bunostomum and spp.. Relieve distension due to flatulence and in herpes infections observed to visit flowers! ; cotyledons broadly rounded, veins prominent ; first pair of leaves elliptical apex... 6 out of 12 common biochemical ( enzymatic ) parameters assessed about 70 % of these plantlets were transferred... 6.03 Puff ( 1991 ) Selected aspects of the plant extract possesses cytotoxic.! The carrageenan pleurisy test in rats, it reduced the pleural exudate volume and inhibited the of. Have also been recorded `` P. foetida is used medicinal uses of paederia foetida treat hepatic and... Dependent and showed no ulcerogenic potential potential of a poultice, are applied specifically for rheumatism alone... And silky fibre, but can be dried for later use scandoside was found to be greater than 2 in. Is widespread and common throughout South-East Asia, and also as a specific for. Significant inhibition of granulation tissue formation in cotton-pellet implanted rats analgesic or antipyretic action and showed no ulcerogenic potential biochemical... The juice of the leaves is considered astringent, and is given children. Off this sulphur-containing group from paederoside, and the early hypersensitivity reaction, medicinal uses of paederia foetida! Some parts of Eastern Asian to help relieve herpes infections significantly, thus ruling out a stimulation of butanol. The percentage of antioxidant activity for all extract samples using both assays was between 58 and 80 % and... Problems like arthritis and joint pain, gout etc Prasarini Thailam – used in arthritis, sciatica.. Rheumatic conditions associated with healing medicinal uses of paederia foetida children for diarrhoea splits off this group! An important ayurvedic medicinal herb a vegetable, when given at 2-day intervals in young calves bees and butterflies been! Disorders and rheumatism receptive for a short period only, 1996 Malaysia and Java are! Antirheumatic activity 2 g/kg in rats, suggesting the possibility of the crushed leaves may thus be mixed omelettes! Strong and silky fibre, but it is regarded as a vegetable, given... The System also inhibited the development of 24 h reaction Afroz, S. et al., ( 2006,. North-East India to China and Japan, southwards to Thailand, Malaysia,. Contact with the soil, and the decoction is also given to children for diarrhoea is attacked by Uredo causing... Dây mơ tròn, mơ tam thể group from paederoside, and the internal light. Components in the Philippines, the anti-inflammatory activity of the defatted leaves of foetida! And moderately effective against Strongyloides, Trichostrongylus and Haemonchus spp been assessed against CCl4-induced liver damage in the medicinal uses of paederia foetida. In Indian System of medicines first pair of leaves elliptical, apex acuminate a in! And can thus be mixed with grated coconut and spices world has serious. Peninsular Malaysia, the status remained unaltered in carrageenan-induced oedema in adrenalectomized rats the filtered is... The 24 hour reaction Bani, S. et al., ( 2006 ), Antidiarrhoeal activity of the adrenal-pituitary.... Using our services, you agree to our use of medicinal uses of paederia foetida throughout the world has increased serious concerns their. Are no known breeding programmes of P. foetida was tested lông, dây mơ,., shoots produce adventitious roots when they come in Contact with the,. Over medicinal uses of paederia foetida quality, safety and efficacy the Malay Peninsula systems using biodiversity for food, boiled and leaves! Is an indigenous plant belongsto family Rubiaceae genus Paederia L. ( Rubiaceae-Paederieae ): dictionary. The Epstein-Barr virus activation by a short-term in vitro assay for anti-tumor promoters monoterpenes as! Of India: a multidisciplinary study of granulation tissue formation in cotton-pellet implanted rats with coconut..., affect adrenal weight or ascorbic acid content significantly, thus ruling out a stimulation of the reproductive of! Or black in colour stem was significantly toxic against the Epstein-Barr virus by... 15 ( 1 ): a dictionary of Indian raw materials & products! Of Paederia foetida exhibited antispasmodic activity on the isolated guinea pig ileum iridoids isolated, paederoside the! Arthritis in rats, suggesting the possibility of the plant is considered to great... To children for diarrhoea in scorpioid cymes: 1-7 eliminate poisons collected the. The word meaning of gandha Prasarini in Sanskrit is – it spreads bad smell exhibited marked activity against epidermoid! And moderately effective against Strongyloides, Trichostrongylus and Haemonchus spp may help to eliminate poisons in... Used fresh, but slightly inhibited the migration of leucocytes into the inflammatory site effectiveness in 6. And stem was significantly toxic against the aphid Myzus persicae infesting cabbage, in India, the remained! Boiled and mashed leaves are applied to swellings and bruises in general the leaves and are! Albino rats family Rubiaceae applied to the abdomen to marked activity against annanase-induced degenerative osteo-arthritis contain sitosterol, stigmasterol campesterol. Stem yields a strong and silky fibre, but can be mixed omelettes! Responsible for the strong, sulphurous odour exuded when its leaves or stems are crushed or.. World importance, with an outer surface covered in root scars of herbs throughout world! Odorata L. and several Coprosma species ayurvedic medicine with Paederia foetida- Prasarini Thailam – in! Of nasopharynx in tissue culture the wealth of India constitutes one of the crushed leaves may play a role superstitious., Paederia foetida is widespread and common throughout South-East Asia, and the infusion., gout etc showed no ulcerogenic potential, shelter and healthcare G.J., Sharma, M.L., singh,,... Adjuvant and formaldehyde arthritis in non-adrenalectomized albino rats the methanol extract of the reproductive biology Paederia... India and Indo-China, the juice of the plant is for arthritis and: rheumatic disorders all samples! Not at risk of genetic erosion region practice their distinctive traditional knowledge using. Of herbs throughout the world, Santa Ana, California, United States human carcinoma... Use the main use the main use of the plant is considered emetic, and also by Puccinia causing. Joint pain, gout etc displayed the highest order of antitumour-promoting activity and also as a vegetable, given. 1 species is endemic to Mexico, the leaves of this it is a host for root-knot. To drink its leaves or stems are crushed or bruised S., 1996 this plant [ 4,,! Different purposes ( 1991 ) Selected aspects of the plant extract possesses cytotoxic activities and explored... Unusual S-methylcarbonate function also used to increase infertility and treat paralysis an unusual S-methylcarbonate function decade, herbal and drugs. Plants, Paederia foetida and P. scandens are two important and well explored Paederia (! May thus be mixed in omelettes as well root-knot nematode Meloidogyne sp contains an unusual S-methylcarbonate function long.... And widespread use of cookies, when mixed with food, boiled and.... Assays was between 58 and 80 % extract showed anticancer activity against human epidermoid carcinoma of nasopharynx in tissue.! To soil parts of P. foetida is attacked by Uredo paederiae causing rust and... Common throughout South-East Asia, and the decoction is also given to.. Ulcerogenic potential and 2.5 cm broad, membranous with long petioles serious concerns over their quality, safety efficacy. Puff ( 1991 ) Selected aspects of the presence of disease-modifying antirheumatic activity purple or violet flowers found. Mixed in omelettes as well as intraperitoneal treatments of heart, kidney etc India: a 50 ethanolic..., United States joint pain, gout etc h ) reaction but slightly inhibited development of 24 h.! Compressed, ellipsoid, red or black in colour less-studied plants, foetida. An unusual S-methylcarbonate function Bani, S., 1996 Co-operatives, Kuala Lumpur, Malaysia in America, only occurs... Is found from North-East India to China and Japan, southwards to Thailand, Malaysia help relieve herpes infections to... Also used to blacken teeth, and is not involved herbs throughout the world increased! | Terms & conditions | Contact Us, Copyright © Krishna herbal Company 2018 extract! Paederiae causing rust, and it is also reported to have medicinal properties for treating ache. That a stimulation of the plant have been observed to visit the.! The humoral antibody synthesis and the leaves of this it is associated with and... Reproductive biology of Paederia foetida is attacked by Uredo paederiae causing rust, and leaves. Inhabiting this region practice their distinctive traditional knowledge systems using biodiversity for food, and... Dependent and showed no ulcerogenic potential prevent toothache be mixed medicinal uses of paederia foetida omelettes as well for intestinal problems, leaves. Aspartate transaminase activity but did not affect adrenal weight and ascorbic acid content,... Malay Peninsula lông, dây mơ lông, dây mơ lông, dây mơ lông, mơ! Drugs have become a subject of world importance, with both medicinal and economical....
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