For more information about this message, please visit this page: Agency for Toxic Substances & Disease Registry, 2-Butoxyethanol and 2-Butoxyethanol Acetate, Health Effects of Exposure to Substances and Carcinogens, Community Environmental Health Education Presentations, Case Studies in Environmental Medicine (CSEM), Toxicology Curriculum for Communities Trainer's Manual, Compendium of Papers on MRLs and Health Effects, Agency for Toxic Substances and Disease Registry. -, Toxicol Appl Pharmacol. In humans, 100 ppm (69 mg/kg bw/day) resulted in ocular and respiratory Irritation, altered taste and nausea (Carpenter et al., 1956). DIPROPYLENE GLYCOL BUTYL ETHER . some . Starek, A., Szymczak, W. and Zapór, L. (2008) Hematological effects of four ethylene glycol monoalkyl ethers in short-term repeated exposure in rats. The substance may cause effects on the central nervous system, blood, kidneys and liver. (1993) Technical report on toxicity studies of ethylene glycol ethers 2-methoxyethanol, 2-ethoxyethanol, 2-butoxyethanol administered in drinking water to F344/N rats and B6C3F1 mice. Ethylene Glycol Ethers Group - information sheet - Canada.ca -. -, Nature. (USCG, 1999) 4 Fukushima Medical University. 1. Note: Javascript is disabled or is not supported by your browser. 1979 Jan;21(1):29-35 2-butoxyethanol may also be listed as ethylene glycol monobutyl ether, ethylene glycol butyl ether, Butyl Cellosolve, ethylene glycol n-butyl ether, butyl Oxitol, Dowanol EB, glycol butyl ether, Polysolv, and Ektasolve EB. Ethylene Glycol Monobutyl Ether; Community Right-To-Know Toxic Chemical Release Reporting, 60818-60825 [2015-25674] No harmful effects were seen on their lungs or hearts. ICSC Routes of Exposure and Symptoms. Int J Toxicol. 2-Butoxyethanol (ethylene glycol monobutyl ether): Target Organs and Levels of Evidence for TR-484 Toxicology and Carcinogenesis Studies of 2-Butoxyethanol (CASRN 111-76-2) in F344/N Rats and B6C3F1 Mice (Inhalation Studies) 2-BE itself is not commercially produced in Canada. Environ Health Perspect. NIOSH Criteria for a Recommended Standard. 2-Butoxyethanol (2-BE), also known as ethylene glycol monobutyl ether, is a clear liquid with an ether-like odour. Acute (short-term) exposure of humans to ethylene glycol by ingesting large quantities causes three stages of health effects… The RfD is an estimate (with uncertainty … The information in this MRL serves as a screening tool to help public health professionals decide where to look more closely to evaluate possible risk of adverse health effects from human exposure. It is also used in liquid soaps, cosmetics, industrial and household cleaners, and dry-cleaning compounds. The main systemic adverse effects of 2-butoxyethanol are on the haematopoietic system (haemolytic effects), followed by possible teratogenic and testicular effects. Diethylene Glycol Poisoning OBJECTIVES To investigate the effects of ethylene glycol monomethyl ether (EGME) on haematology and reproduction in exposed workers. Studies on ethylene glycol alkyl ethers and related compounds … Occupational exposure limits for ethylene glycol monobutyl ether, isoprene, isopropyl acetate and propyleneimine, and classifications on carcinogenicity, occupational sensitizer and reproductive toxicant ... 2 Japan Industrial Safety and Health Association. DIPROPYLENE GLYCOL BUTYL ETHER can be found in 39 products. People who swallowed large amounts of cleaning agents containing 2-butoxyethanol have shown breathing problems, low blood … During 2003, the production of EGBE in the European Union was approximately 161,000 tonnes. Would you like email updates of new search results? 2017 Jul 27;59(4):364-366. doi: 10.1539/joh.17-0148-OP. Precautions. In view of recent findings with other chemically related glycol ethers, particular attention has been given to possible adverse effects on blood and testicular tissue. significantly higher ethylene glycol monobutyl ether concentrations than the control group (geometric mean value: 0.14vs. U.S. Department of Health and Human Services, Public Health Service, National Institutes of Health… Diethylene glycol ethers were absorbed more slowly than the corresponding ethylene glycol ethers. | 2-Butoxyethanol is an organic compound with the chemical formula BuOC 2 H 4 OH (Bu = CH 3 CH 2 CH 2 CH 2).This colorless liquid has a sweet, ether-like odor, as it derives from the family of glycol ethers, and is a butyl ether of ethylene glycol.As a relatively nonvolatile, inexpensive solvent, it is used in many domestic and industrial products because of its properties as a surfactant. It is liable to form peroxides on exposure to air and light. 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